By N. T. Kärki
This quantity has 24 chapters divided into 4 sections. After discussing the developmental elements of drug metabolism and enzyme inhibitors of microbial starting place, this e-book turns its awareness to the interrelationships between quite a few enzyme platforms and physiological techniques which are identified to impact the distribution and metabolism of substances. this article additionally highlights the response mechanisms of cytochrome P-450; the hyperlink among microsomal drug oxidation and glucuronidation; and the pharmacokinetics of the 1st cross impression. The reader is then brought to the toxicity of foodstuff ingredients and the toxicity and metabolism of plasticizers and plastics. This quantity concludes with a bankruptcy that evaluates a number of the biochemical and pharmacologic results of di-2-ethylhexyl phthalate (DEHP).
This publication will entice scientists representing all of the significant parts of pharmacology, together with medical pharmacology and toxicology, in addition to to internists, psychiatrists, neurologists, and anesthesiologists.
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Extra info for Mechanisms of Toxicity and Metabolism: Proceedings of the Sixth International Congress of Pharmacology: 6th, v. 6 (Proceedings of the Sixth International Congress of Pharmacology ; v. 6)
Mechanisms of Toxicity and Metabolism: Proceedings of the Sixth International Congress of Pharmacology: 6th, v. 6 (Proceedings of the Sixth International Congress of Pharmacology ; v. 6) by N. T. Kärki